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Toniquiro said:
IGF-1 LR3 is reconstituted using a combination of acetic acid (typically 0.6%–1% AA in bacteriostatic water) to ensure its long-term stability and prevent protein degradation. This combination is crucial for maintaining the peptide's potency, allowing for refrigerated storage, unlike other preparations that degrade.
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I was hoping Driada would provide AA in the packaging or as an alternative.
 
xccdf said:
IGF-LR3 and IGF-DES degrades super rapidly, almost instantly in BAC.

Consider offering Acetic Acid (0.6%) for:

* IGF-1 LR3
* IGF-1 DES
* MGF (Mechano Growth Factor)
* PEG-MGF (Pegylated Mechano Growth Factor)
* Follistatin 344
* Follistatin 315

If you mix those with BAC your just throwing your money in the trash.

Currently in Europe we are ordering it from the states via Amazon.
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I’m not sure that 0.9% benzyl alcohol will destroy these peptides, but yes, they are more sensitive to this kind of exposure—at least according to ChatGPT. No precise experiments have been conducted to empirically prove this.
 
Driadashop said:
Por favor dime la fuente de tu información, esto es muy interesante.
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Hola pues viendo más información sobre la tesamorelina,creo queo mismo no vale la pena . Sale muy muy cara ,precio medio 60 euros por 2mg y su protocolo es de 1 a 2 mg por inyección. Te dejo unos de los sitios más interesantes donde podrás ver desde protocolos. Es el péptido más caro ya que tiene 44 aminoácidos y si lo utilizas como realmente te indican en fuentes fiables sale más caro que la HGH . Unos de los sitios donde puedes ver es Doctormed.com
 
Toniquiro said:
Hola pues viendo más información sobre la tesamorelina,creo queo mismo no vale la pena . Venta muy muy cara, precio medio 60 euros por 2 mg y su protocolo es de 1 a 2 mg por inyección. Te dejo unos de los sitios más interesantes donde podrás ver desde protocolos. Es el péptido más caro ya que tiene 44 aminoácidos y si lo utiliza como realmente te indican en fuentes confiables venta más caro que la HGH. Unos de los sitios donde puedes ver es Doctormed.com
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Perdón Doctorgmed
 
Driadashop said:
I’m not sure that 0.9% benzyl alcohol will destroy these peptides, but yes, they are more sensitive to this kind of exposure—at least according to ChatGPT. No precise experiments have been conducted to empirically prove this.
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The reason IGF-1 (LR3 and DES) need Acetic Acid (AA) is because every peptide has an Isoelectric Point. This is the point where the molecule has a neutral or zero electrical charge. The pI of IGF-1 is naturally basic at around 8.4~. When it is in a solution with a pH close to its pI, the molecules lose their electrical repulsion and start clumping together (aggregation) and can physically stick to the spores of the glass vial (adsorption). Sounds a bit wild, but you will lose the peptide to the glass.

When in 0.6% AA, the pH drops to roughly 2.5 to 3.0. In this highly acidic environment, you are putting the molecules far away from it's pI, so they become heavily positively charged. Because positive repels positive, the molecules repel each other and essentially bounce off the glass.

** And going back to Follistatin - I was wrong. The molecule is a very large complex glycoprotein and must maintain that specific 3D folded shape to physically grab and neutralize Myostatin in your body. This molecule is held together very a delicate electrostatic bond (salt bridges) and hydrogen bonds. Where I was wrong was when you introduce this protein into a highly acidic environment (pH less than 3.0), the influx of hydrogen ions (H+) disrupt and break the salt bridges causing it to basically... unfold. This is called denaturation. So do NOT add Follistatin to something that will make it lose its 3D shape. So, yes I have went back and updated my library of notes. I was wrong on that one.

1773073713865.png

Beautiful picture huh (don't laugh). AA hurts, but you can get used too it over time. There is a method called backloading where you draw your IGF analog out of the reconstituted AA, getting your precise dose, then drawing up some BAC right before injecting if you are really trying to avoid to punch of AA.
 
xccdf said:
The reason IGF-1 (LR3 and DES) need Acetic Acid (AA) is because every peptide has an Isoelectric Point. This is the point where the molecule has a neutral or zero electrical charge. The pI of IGF-1 is naturally basic at around 8.4~. When it is in a solution with a pH close to its pI, the molecules lose their electrical repulsion and start clumping together (aggregation) and can physically stick to the spores of the glass vial (adsorption). Sounds a bit wild, but you will lose the peptide to the glass.

When in 0.6% AA, the pH drops to roughly 2.5 to 3.0. In this highly acidic environment, you are putting the molecules far away from it's pI, so they become heavily positively charged. Because positive repels positive, the molecules repel each other and essentially bounce off the glass.

** And going back to Follistatin - I was wrong. The molecule is a very large complex glycoprotein and must maintain that specific 3D folded shape to physically grab and neutralize Myostatin in your body. This molecule is held together very a delicate electrostatic bond (salt bridges) and hydrogen bonds. Where I was wrong was when you introduce this protein into a highly acidic environment (pH less than 3.0), the influx of hydrogen ions (H+) disrupt and break the salt bridges causing it to basically... unfold. This is called denaturation. So do NOT add Follistatin to something that will make it lose its 3D shape. So, yes I have went back and updated my library of notes. I was wrong on that one.

View attachment 3567
Beautiful picture huh (don't laugh). AA hurts, but you can get used too it over time. There is a method called backloading where you draw your IGF analog out of the reconstituted AA, getting your precise dose, then drawing up some BAC right before injecting if you are really trying to avoid to punch of AA.
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Thank you very much for your help. Which of the peptides from the list require AA?
 
xccdf said:
IGF-LR3 and IGF-DES degrades super rapidly, almost instantly in BAC.

Consider offering Acetic Acid (0.6%) for:

* IGF-1 LR3
* IGF-1 DES
* MGF (Mechano Growth Factor)
* PEG-MGF (Pegylated Mechano Growth Factor)
* Follistatin 344
* Follistatin 315

If you mix those with BAC your just throwing your money in the trash.

Currently in Europe we are ordering it from the states via Amazon.
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Could you please PM me with the link to amazon with igf?😊
 
fluffyde said:
Could you please PM me with the link to amazon with igf?😊
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I don't get IGF from Amazon sadly, the LR3 and DES comes from reputable UGL's. As in tested over and over again labs. But you can PM me with any questions and I'd be glad to help. IGF-LR3 is the most loved and hated substance I've seen people take. It works wonderfully for some, they swear by pre-workout injections to shuttle nutrients. Some feel nothing but super PIP. You have to take a broad view of your entire body, gender, age.. I could go on. Just PM me.
 
Hola, vamos a ver si driada se anima a sacar combos de péptidos como ya casi todas las marcas reconocidas tienen.
BPC 157+TB500 , combos de ghrp +ghrh en fln os animo que la gente os lo agradecerá.
 
Toniquiro said:
Hola, vamos a ver si driada se anima a sacar combos de péptidos como ya casi todas las marcas reconocidas tienen.
BPC 157+TB500 , combos de ghrp +ghrh en fln os animo que la gente os lo agradecerá.
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BPC and TB combos do work well, but the dosages are not 1:1. If you get a vial from from China (Sig) with a 5mg and 5mg combo, that is not ideal at all. Sig is reopening soon so hopefully Driada can buy in batches. But dont mix TB and BPC without the correct ratios for your goal.
 
xccdf said:
Las combinaciones de BPC y TB funcionan bien, pero las dosis no son 1:1. Si recibes un vial de China (Sig) con una combinación de 5 mg y 5 mg, no es lo ideal. Sig reabrirá pronto, así que esperamos que Driada pueda comprar al por mayor. Pero no mezcles TB y BPC sin las proporciones correctas para tu objetivo.
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xccdf said:
Las combinaciones de BPC y TB funcionan bien, pero las dosis no son 1:1. Si recibes un vial de China (Sig) con una combinación de 5 mg y 5 mg, no es lo ideal. Sig reabrirá pronto, así que esperamos que Driada pueda comprar al por mayor. Pero no mezcles TB y BPC sin las proporciones correctas para tu objetivo.
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No te preocupes porque ahora no utilizamos combinaciones de ningún péptido. Pero ninguna marca que he visto y alguna muy confiable es china. Son europeos, indias y americanas. Es cierto que el BPC 157+TB 500 hay marcas con 5/5 y otras 10/10 pero lo que la gente hace mal es la reconstitución ya que no se hace con 1 ml. La de 5/5 se hace con 2ml y la de 10/10 con 3ml ahí está el secreto de utilizar los péptidos correctamente.
 
Toniquiro said:
Don't worry, we don't use any peptide combinations now. But none of the brands I've seen, even some very reliable ones, are Chinese. They're European, Indian, and American. It's true that some brands of BPC 157+TB 500 are 5/5 and others 10/10, but what people are doing wrong is the reconstitution, since it's not done with 1 ml. The 5/5 version is made with 2 ml and the 10/10 version with 3 ml; that's the secret to using peptides correctly.
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Brother, all affordable materials come from China for this specific market. Even the deep Indian markets source their raws from China.
 
xccdf said:
Hermano, todos los materiales asequibles para este mercado específico provienen de China. Incluso los mercados más importantes de la India se abastecen de materias primas en China.
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Lo sé perfectamente que el polvo de esteroides péptidos viene de china. Pero me refería a marcas . Gracias igualmente llevo muchísimo tiempo en esto. Cuidate
 
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