Retatrutide Dosing - First Hand Experience?

[xccdf]

Reading theough the clinical trials, and anecdotal results posted online, I have got mixed results on the dosing and ramping up of Retatrutide to the minimal effective dose for results.

Has anyone taken this before and what was your ramping schedule like? Where did you end up?

I have read 1mg for 4 weeks, the ramping to 2mg for 4 weeks, then 5mg for 4 weeks, then 7.5mg for 4 weeks and so on.

Just looking for anyone with experience. I personally think the 1mg dosage is probably a wasted step (except to test for allergic reactions or pancreas tolerance).

 

[Alireza]

I would start at 1 mg and see how your body responds. The dosages mentioned in the clinical data are for people with obesity and type 2 diabetes.

Some people need more than others, so it’s best to find the dose that gives you the most benefit.

 

[Baugaros]

Hello, I am on 5mg of RETA, I used up to 1mg of SEMA for 5 months (-20kg) and I was stuck, then I added 0.5mg SEMA + 2mg for 2 weeks and I barely lost more weight, and hunger came back. Then I increased it to 5mg, I've been on it for 4 months (-15kg). (Total 35kg with a 13/14%BF)

I don't increase the dose because with 5mg I already find it hard to eat and I lose 300/400g of weight weekly. In April, I will do 12/16 weeks at 500mg of Testosterone Cypionate + 2.5mg RETA, and see results after 12 months of preparation and returning to the gym (having been inactive for 8 years and weighing 110kg with 40% BF).



Any questions you have...

 

[Pablo_Testobar]

I'm currently using 10 mg of Reta per week and don't want to go higher. I started with 2 mg for four weeks and then tapered up every four weeks until I reached 8 mg per week. I stayed at 8 mg for eight weeks, and now I just want to gain some experience with 10 mg of Reta for a few weeks before going back to 8 mg. I also have some Sema on hand because Reta doesn't affect my appetite much, so I inject 10 mg of Reta on Sundays and 0.66 mg of Sema on Wednesdays. I fill both into reusable insulin pens.

You should start with 1 mg and stay there for at least four weeks to see how you react. The leaner you are, the stronger it hits, so only taper up when you feel like it's not enough anymore.

 

[Zorroxd]

I mostly used tirzepatide but i also had a great spot on 5 mg/week except after id say 8-10 weeks where id start to feel hungry a lot 5 days post injection while 2.5 didnt do much for me.
i then went up to 7.5 which was a bit to much had some nausea that week and dropped my next injection to 6.25 mg which was better again and kept loosing weight.
I guess you just have to find your sweet spot each doing increase atleast thats how i felt.
also the sickness isent bad its someother kind of feeling sick atleast for me id just take some Dimenhydrinate and id be all good.

 

[Baugaros]

Actualmente uso 10 mg de Reta a la semana y no quiero aumentar la dosis. Empecé con 2 mg durante cuatro semanas y luego fui aumentando la dosis cada cuatro semanas hasta llegar a 8 mg semanales. Me mantuve en 8 mg durante ocho semanas, y ahora solo quiero adquirir experiencia con 10 mg de Reta durante unas semanas antes de volver a 8 mg. También tengo Sema a mano porque Reta no me afecta mucho el apetito, así que me inyecto 10 mg de Reta los domingos y 0,66 mg de Sema los miércoles. Los inyecto en plumas de insulina reutilizables.

Debes empezar con 1 mg y mantenerlo durante al menos cuatro semanas para ver cómo reaccionas. Cuanto más delgado estés, más fuerte te hará el efecto, así que solo disminuye la dosis cuando sientas que ya no es suficiente.

I
Interesting, how much did you weigh and what was your BF when you were using 10mg?

I'm asking because after two or three weeks at 5mg, I've lost all desire to eat. At first, when switching from SEMA to RETA, my appetite returned (especially between meals). But when I reach 5mg... I don't eat anything, and I barely lose any weight, 300g/week, and I sacrifice muscle due to the lack of appetite...

I don't need it, but if I did, I think I couldn't increase the dose, because I'm sure I would start to feel bad, I'm almost at my limit, the first and second day after injecting 5mg, I have stomach discomfort and a drop in energy... I will be at +/-15% BF.

In a few weeks, I will drop to 2.5mg or less, to add 500mg of Testosterone and be able to eat the sufficient macros for the 12/16 week cycle...

Let's see how it turns out after a year, I'll let you know.


Greetings

En unas semanas, bajaré a 2,5 mg o menos, para agregar 500 mg de testosterona y poder comer suficientes macros para el ciclo de 12/16 semanas...

A ver qué tal va dentro de un año, os cuento.


Saludos